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KMID : 0379520020180020149
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한국독성학회지
2002 Volume.18 No. 2 p.149 ~ p.157
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3 Months Repeated Dose Toxicity Studies of the Bamboo Salt(Jukyum) in Rats
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Kim Jun-Gyou
Seo Kyung-Won
Lee Bong-Hun
Park Mi-Kyung
Park Chang-Won
Shin Dong-Whan
Hong Choong-Man
Han Beom-Seok
Kim Yun-Jung
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Abstract
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Though the bamboo salt, called as "JUKYUM" has been widely used in Korea as panacea, it’s toxicity was not screened completely. To investigate the toxicity of bamboo salt, we compared with the toxicity of crude salt and reagent-grade NaCl by performing repeated dose (3 month’s) oral toxicity test in SD rats. Crude salt, natural sun-dried salt (crude salt) production, was purchased from the western seashore of Korean peninsular and reagent-grade NaCl was purchased from Sigma company. Results of repeated dose oral toxicity tests for 3 months (bamboo salt; 750, 1500, 3000 mg/kg/day, crude salt : 3000 mg/kg/day, reagent-grade NaCl; 3000 mg/kg/day) suggested that the bamboo salt treated group show no significant toxicological findings with body weights and organ weighs changes, and hematological, serum bio-chemical and histopathological findings compared with other groups.er groups.
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KEYWORD
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Bamboo salt (JUKYUM), Repeated dose toxicity, Rats
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